张欢
Huan Zhang
长聘教轨副教授
Email: zhang_huan@sjtu.edu.cn
教育背景
2005-2009 鲁东大学，学士
2009-2014 中国科学院大学上海应用物理研究所，博士
工作经历
2014-2017 中国科学院上海高等研究院，助理研究员
2017-2020 加州大学伯克利分校，博士后
2020-2022 暨南大学, 预聘教授
2022-至今 上海交通大学农业与生物学院，长聘教轨副教授
研究方向
可编程核酸材料设计构建及人工细胞
核酸分子递送及基因调控
RNA农药
科研项目
国家自然科学基金面上、青年项目
国家科技部重点研发计划课题
上海市浦江人才、上海市合成生物中心概念验证项目
代表性论文专著
Jingyi Ye, Ao Liu, Hui Lv*, Chenyun Sun, Fei Wang, Huan Zhang* and Honglu Zhang*. Nick-and-Digest Strategy for Programmable Circular ssDNA Production and Scalable DNA Origami Assembly. JACS Au, 2025, 5, 5312−5321.
Yi Xu#, Yao Luo#, Xiaoyun Lu#, Jingyi Ye, Zeyu Chen, Yao Hu, Chen Shen, Bin Zhao, Erfeng Kou, Jie Deng, Chunhai Fan, Huan Zhang* and Honglu Zhang*. Dynamic modulation of multicellular interactions via ATP-dissipative DNA assembly. JACS, 2025, 147,28277−28288.
Zeyu Chen#, Xu Chen#, Dan Lu, Huating Kong, Jingyi Ye, Chunhai Fan, Honglu Zhang* and Huan Zhang*. Engineering Liquid Hierarchical Materials with DNA-Programmed Spherical Nucleic Acids. Advanced Science, 2025, 12, e04471 (1-12).
Qianqian Hu#, Erfeng Kou#, Xiuzhen Liao, Ruiyi Qiu, Qi Tang, Huan Zhang*, Yun Zheng*, Ji Yang* and Binglian Zheng*. Nanoparticle Delivery of Antisense miR162 Inhibits Invasive Habitat Adaption of Alternanthera Philoxeroides. Advanced Science, 2025, 2416747.
Erfeng Kou, Zhongxu Luo, Jingyi Ye, Xu Chen, Dan Lu, Markita P. Landry, Honglu Zhang and Huan Zhang*. Sunlight-Sensitive Carbon Dots for Plant Immunity Priming and Pathogen Defense. Plant Biotechnology Journal, 2025, 1-12.
Xiaoyue Xu, Erfeng Kou, Kunyu Zhang*, Honglu Zhang*, Huan Zhang*. Programmable DNA-based biomaterials for bone tissue engineering, Fundamental Research, 2025, 5, 1384–1400.
Yao Hu, Zhongxu Luo, Zhilei Ge, Qian Li, Peihui Yang, Honglu Zhang* and Huan Zhang*. Morphology Dictated Immune Activation with Framework Nucleic Acids. Small, 2023, 23034: 1-10.
Huan Zhang#, Natalie S Goh#, Jeffrey Wang, Gozde S Demirer, Salwan Butrus, So-Jung Park, Markita Landry*. Nanoparticle Cellular Internalization is Not Required for RNA Delivery to Mature Plant Leaves. Nature Nanotechnology, 2022, 17, 197-205.
Huan Zhang#, Honglu Zhang#, Gozde S. Demirer, Eduardo González-Grandío, Chunhai Fan and Markita P. Landry*. Engineering DNA nanostructures for siRNA delivery in plants. Nature Protocols, 2020, 15, 3064-3087.
Huan Zhang#, Gozde S. Demirer#, Honglu Zhang#, Tianzheng Ye, Natalie S. Goh, Abhishek J. Aditham, Francis J. Cunningham, Chunhai Fan and Markita P. Landry*. DNA Nanostructures Coordinate Gene Silencing in Mature Plants. PNAS, 2019,116, 15:7543-7548.
