教育背景

• 1999-2004 中国科学技术大学，学士

• 2004-2009 纽约大学（New York University），博士

工作经历

• 2009-2015  耶鲁大学（Yale University），博士后

• 2015-2021  复旦大学，研究员

• 2022-至今  上海交通大学化学化工学院，研究员

研究方向

• DNA纳米自组装

• DNAzyme探针

• 肿瘤标志物筛选

科研项目

• 科技部重点研发计划，2020YFA0908901，微纳生物机器人的定向合成和诊疗应用（课题一），2020.11-2025.10，主持

• 国家自然科学基金重大研究计划培育项目，91859104，开发基于核酸适配体的新型探针用于肿瘤的标志物识别和诊治，2019.01-2021.12，主持

• 国家自然科学基金面上项目，21673050，DNA纳米骨架的组装及其在生物和材料学中的应用，2017.01-2020.12，主持，已结题

代表性论文专著

1. Yang Yang¥; Zhenyong Wu¥; Laurie Wang; Kaifeng Zhou; Kai Xia; Qiancheng Xiong; Longfei Liu; Zhao Zhang; Edwin R Chapman; Yong Xiong; Thomas J Melia; Erdem Karatekin; Hongzhou Gu*; Chenxiang Lin*. “Sorting liposomes of distinct sizes by DNA-brick assisted centrifugation.” Nature Chemistry 2021, 13, 335-342.

2. Youli Jia¥; Liman Chen¥; Jin Liu; Wei Li; Hongzhou Gu*. “DNA Catalyzed Efficient Production of Single-stranded DNA Nanostructures.” Chem 2021, 7, 4, 959-981.

3. Qingting Li; Zongxuan Tong; Yichun Cao; Hongzhou Gu*. “DNAs catalyzing DNA nanoconstruction.” Chem 2021, 7, 10, 2556-2568.

4. Canyu Zhang; Qingting Li; Tianbin Xu; Wei Li; Yungang He; Hongzhou Gu*. “New DNA-hydrolyzing DNAs isolated from an ssDNA library carrying a terminal hybridization stem.” Nucleic Acids Research 2021, 49, 11, 6364-6374.

5. Xinyu Du¥; Xiaoqin Cheng¥; Wei Li; Zhilei Ge; Chunjiu Zhong; Chunhai Fan; Hongzhou Gu*. “Engineering allosteric ribozymes to detect thiamine pyrophosphate in whole blood.” Analytical Chemistry 2021, 93, 9, 4277-4284.

6. Tianbin Xu¥; Canyu Zhang¥; Kai Xia; Wei Li; Yichun Cao; Hongzhou Gu*. “Small DNAs that bind nickel(II) specifically and tightly.” Analytical Chemistry 2021, 93, 45, 14912-14917.

7. Qingting Li; Shu Zhang; Wei Li; Zhilei Ge; Chunhai Fan; Hongzhou Gu*. “Programming CircLigase catalysis for DNA rings and topologies.” Analytical Chemistry 2021, 93, 3, 1801-1810.

8. Dong-Jie Tang¥; Xinyu Du¥; Qiang Shi¥; Jian-Ling Zhang¥; Yuan-Ping He; Yan-Miao Chen; Zhenhua Ming; Dan Wang; Wan-Ying Zhong; Yu-Wei Liang; Jin-Yang Liu; Jian-Ming Huang; Yun-Shi Zhong; Hongzhou Gu*; Ji-Liang Tang*. “A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA.” Nature Communications 2020, 11, 2794, 1-11.

9. Kai Xia; Jianlei Shen; Qian Li; Chunhai Fan*; Hongzhou Gu*. “Near-Atomic Fabrication with Nucleic Acids.” ACS Nano 2020, 14, 1319-1337.

10. Qinqin Hu¥; Hua Li¥; Lihua Wang; Hongzhou Gu*; Chunhai Fan*. “DNA Nanotechnology Enabled Drug Delivery systems.” Chemical Reviews 2019, 119, 6459-6506.